Aldehyde Capture Ligation for Synthesis of Native Peptide Bonds
Raj M, Wu H, Blosser S, Vittoria M, Arora P. Aldehyde Capture Ligation for Synthesis of Native Peptide Bonds. Journal Of The American Chemical Society 2015, 137: 6932-6940. PMID: 25966041, DOI: 10.1021/jacs.5b03538.Peer-Reviewed Original ResearchConceptsBond formationAmide bond formationNative peptide bondChemoselective reactivityChemoselective reactionAmine terminusIntramolecular reactionSynthetic proteinsPeptide bondReactionAmino acid residuesBioconjugatesFormationAcid residuesAldehydesCarboxylBondsAminesSynthesisReactivityFragmentsPeptidesResidues
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