Comparative Performance of Machine Learning Models in Reducing Unnecessary Targeted Prostate Biopsies
Chen F, Esmaili R, Khajir G, Zeevi T, Gross M, Leapman M, Sprenkle P, Justice A, Arora S, Weinreb J, Spektor M, Huber S, Humphrey P, Levi A, Staib L, Venkataraman R, Martin D, Onofrey J. Comparative Performance of Machine Learning Models in Reducing Unnecessary Targeted Prostate Biopsies. European Urology Oncology 2025 PMID: 39924390, DOI: 10.1016/j.euo.2025.01.005.Peer-Reviewed Original ResearchProstate cancerPrediction of clinically significant prostate cancerClinical dataProstate-specific antigen levelClinically significant prostate cancerProstate magnetic resonance imagingSeverity of prostate cancerCombination of clinical featuresPrediction of csPCaSignificant prostate cancerProstate Imaging-ReportingCore needle biopsyRetrospective analysis of dataDecision curve analysisReducing unnecessary biopsiesProstate cancer diagnosisReceiver operating characteristic curveArea under the receiver operating characteristic curveFalse-negative rateMagnetic resonance imagingPersonalized risk assessmentAntigen levelsNeedle biopsyPatient ageUnnecessary biopsies
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